产品详情
简单介绍：
Anti-phospho-SMC1 (Ser966)抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-phospho-SMC1 (Ser966)抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-phospho-SMC1 (Ser966)
Cat. Number:
Anti-phospho-SMC1 (Ser966)抗体KL-19927R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1B or the protein
Anti-phospho-SMC1 (Ser966)抗体encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. Mutations in this gene result in Cornelia de Lange syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
Also known as:
SMC1 (phospho S966); p-SMC1 (phospho S966); CDLS2; DKFZp686L19178; DXhXs423e; DXS423E; KIAA0178; MGC138332;
Anti-phospho-SMC1 (Ser966)抗体OTTHUMP00000061876; RP6 29D12.1; SB1.8; Segregation of mitotic chromosomes 1; Segregation of mitotic chromosomes like 1; SMC 1; SMC protein 1B; SMC-1-beta; SMC-1B; SMC1; SMC1A; SMC1alpha; SMC1alpha protein; SMC1B; SMC1B_HUMAN; SMC1BETA; SMC1beta protein; SMC1L1; SMC1L2; SMCB; Structural maintenance of chromosome 1 like 1 protein; Structural maintenance of chromosome 1 like 2 protein; Structural maintenance of chromosomes 1A; Structural maintenance of chromosomes 1B; Structural maintenance of chromosomes protein 1B.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, .
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Immunogen: KLH conjugated synthesised
Anti-phospho-SMC1 (Ser966)抗体phosphopeptide derived from human SMC1 around the phosphorylation site of Ser966..
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Predicted Molecular Weight: 136kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-phospho-SMC1 (Ser966)抗体
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-phospho-SMC1 (Ser966)抗体
Optimal working dilutions must be determined by the end user.
