产品详情
简单介绍：
Anti-phospho-CDKN1A (Thr145)抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-phospho-CDKN1A (Thr145)抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-phospho-CDKN1A (Thr145)
Cat. Number:
Anti-phospho-CDKN1A (Thr145)抗体KL-5237R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1.
Anti-phospho-CDKN1A (Thr145)抗体The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and may be instrumental in the execution of apoptosis following caspase activation. Two alternatively spliced variants, which encode an identical protein, have been reported. Two families of cyclin dependent kinase inhibitors (CKIs) have been identified. The p21WAF1/Cip1 family inhibits all kinases involved in the G1/S transition. The p16INK4a family inhibits Cdk4 and Cdk6 specifically.
Also known as:
p21 (phospho T145); p-p21
Anti-phospho-CDKN1A (Thr145)抗体(phospho T145); p21Cip1 (Phospho-Thr145); Activating Fragment 1; CAP20; Cation chloride cotransporter-interacting protein 1; CDK Interacting Protein 1; CDK-interacting protein 1; CDKI; CDKN 1; CDKN1; CDKN1A; CIP1; Cyclin Dependent Kinase Inhibitor 1A; Cyclin-dependent kinase inhibitor 1; Cyclin-dependent kinase inhibitor 1A (P21); Cyclin-dependent kinase inhibitor 1A (p21, Cip1); DNA Synthesis Inhibitor; MDA 6; MDA-6; MDA6; Melanoma Differentiation Associated Protein 6; Melanoma differentiation-associated protein 6; Melanoma differentiation-associated protein; p21; P21 protein; p21CIP1; p21WAF; PIC1; SDI1; SLC12A9; WAF1; Wildtype p53 Activating Fragment 1; Wildtype p53-activated fragment 1.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, .
Anti-phospho-CDKN1A (Thr145)抗体
●
Immunogen: KLH conjugated Synthesised phosphopeptide derived from human CDKN1A around the phosphorylation site of Thr145 [RQ(p-T)S].
●
Predicted Molecular Weight: 18kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be Anti-phospho-CDKN1A (Thr145)抗体determined by the end user.
Not yet tested in other applications.
Optimal working dilutions must be Anti-phospho-CDKN1A (Thr145)抗体determined by the end user.
kl728Hu01 生长分化因子2(GDF2)多克隆抗体 Polyclonal Antibody to Growth Differentiation Factor 2 (GDF2)
kl728Mu01 生长分化因子2(GDF2)多克隆抗体 Polyclonal Antibody to Growth Differentiation Factor 2 (GDF2)
kl729Hu01 癌蛋白诱导转录物3(OIT3)多克隆抗体 Polyclonal Antibody to Oncoprotein Induced Transcript 3 (OIT3)
kl735Hu01 胱天蛋白酶4(CASP4)多克隆抗体 Polyclonal Antibody to Caskle 4 (CASP4)
kl737Hu01 信号传导转录激活因子6(STAT6)多克隆抗体 Polyclonal Antibody to Signal Transducer And Activator Of Transcription 6 (STAT6)
kl744Hu01 泛素D(UBD)多克隆抗体 Polyclonal Antibody to Ubiquitin D (UBD)
kl745Hu01 血小板型磷酸果糖激酶(PFKP)多克隆抗体 Polyclonal Antibody to Phosphofructokinase, Platelet (PFKP)
kl750Hu01 肿瘤坏死因子配体超家族成员13(TNFSF13)多克隆抗体 Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13)
kl750Mu01 肿瘤坏死因子配体超家族成员13(TNFSF13)多克隆抗体 Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13)
kl752Hu01 Ⅰ类主要组织相容性复合体E(MHCE)多克隆抗体 Polyclonal Antibody to Major Histocomklibility Complex Class I E (MHCE)
kl753Hu01 谷氨酸受体相互作用蛋白1(GRIP1)多克隆抗体 Polyclonal Antibody to Glutamate Receptor Interacting Protein 1 (GRIP1)
kl756Hu01 表皮转谷氨酰胺酶(TGM3)多克隆抗体 Polyclonal Antibody to Transglutaminase 3, Epidermal (TGM3)
kl757Hu01 肌动蛋白束蛋白(FSCN)多克隆抗体 Polyclonal Antibody to Fascin (FSCN)
kl758Hu01 核糖核酸酶A3(RNASE3)多克隆抗体 Polyclonal Antibody to Ribonuclease A3 (RNASE3)
