产品详情
简单介绍：
Anti-Calpain 2抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-Calpain 2抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-Calpain 2
Cat. Number:
Anti-Calpain 2抗体KL-1599R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Calpain, and m calpain,
Anti-Calpain 2抗体also known as Calpain 2, are intracellular, calcium dependent cysteine proteases. Mu calpain has a micromolar sensitivity (thus the mu) as compared to the millimolar calcium sensitivity of m calpain. Both Calpains 1 and 2 are composed of an 80 kD subunit and a 30 kD subunit. Whereas the 30 kDa subunit is shared by both enzymes, the larger catalytic subunits are different and exhibit the distinct Ca++ requirements that are suggested by their names.
The calpains have papain like activity, thus the pain nomenclature. Both Calpain 1 and Calpain 2 are ubiquitously expressed, and are countered by the endogenous calpain inhibitor, calpastatin.
Other calpain family members (calpain 94, ncl2, ncl3, etc) have more limited tissue distribution, and perhaps different functions. The calpain family members consist of a common small subunit (Calpain 4), and a large variable subunit. It is not clear that all calpains contain a small subunit. Domains in the large subunit include the amino terminal domain I, the proteinase domain II, domain III, and the EF hand domain IV. The calpains appear to serve multiple physiological roles, and ideas concerning the functions of these enzymes are in a state of rapid flux.
The calpains have papain like activity, thus the pain nomenclature. Both Calpain 1 and Calpain 2 are ubiquitously expressed, and are countered by the endogenous calpain inhibitor, calpastatin.
Other calpain family members (calpain 94, ncl2, ncl3, etc) have more limited tissue distribution, and perhaps different functions. The calpain family members consist of a common small subunit (Calpain 4), and a large variable subunit. It is not clear that all calpains contain a small subunit. Domains in the large subunit include the amino terminal domain I, the proteinase domain II, domain III, and the EF hand domain IV. The calpains appear to serve multiple physiological roles, and ideas concerning the functions of these enzymes are in a state of rapid flux.
Also known as:
Calcium activated neutral
Anti-Calpain 2抗体proteinase 2; Calcium activated neutral proteinase; CALP80; Calpain 2 (m/II) large subunit; Calpain 2 catalytic subunit; Calpain 2 large catalytic subunit; Calpain 2 large subunit; Calpain large polypeptide L2; Calpain M type; Calcium-activated neutral proteinase 2; CALP80; Calpain 2, large [catalytic] subunit; Calpain M-type; Calpain-2 catalytic subunit; Calpain-2 large subunit; CAN2_MOUSE; M-calpain; Millimolar-calpain; Calpain2; CANP 2; CANP L2; CANP2; CANPL 2; CANPL2; CANPml; Capa2; CAPN 2; CAPN2; FLJ39928; M calpain; M calpin; M type; mCANP; Millimolar calpain.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Dog, Cow, Sheep, .
●
Immunogen: KLH conjugated synthetic peptide derived from mouse Calpain 2.
●
Predicted Molecular Weight:
Anti-Calpain 2抗体78kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working Anti-Calpain 2抗体dilutions must be determined by the end user.
Not yet tested in other applications.
Optimal working Anti-Calpain 2抗体dilutions must be determined by the end user.
kl002Hu01 CREB结合蛋白(CREBBP)多克隆抗体 Polyclonal Antibody to CREB Binding Protein (CREBBP)
kl020Mu01 蛋白磷酸酶3调节因子亚基1(PPP3R1)多克隆抗体 Polyclonal Antibody to Protein Phosphatase 3, Regulatory Subunit 1 (PPP3R1)
kl038Hu01 轻肽神经丝蛋白(NEFL)多克隆抗体 Polyclonal Antibody to Neurofilament, Light Polypeptide (NEFL)
kl038Mu01 轻肽神经丝蛋白(NEFL)多克隆抗体 Polyclonal Antibody to Neurofilament, Light Polypeptide (NEFL)
kl039Hu01 围脂滴蛋白5(PLIN5)多克隆抗体 Polyclonal Antibody to Perilipin 5 (PLIN5)
kl040Hu01 围脂滴蛋白4(PLIN4)多克隆抗体 Polyclonal Antibody to Perilipin 4 (PLIN4)
kl040Mu01 围脂滴蛋白4(PLIN4)多克隆抗体 Polyclonal Antibody to Perilipin 4 (PLIN4)
kl041Hu01 围脂滴蛋白3(PLIN3)多克隆抗体 Polyclonal Antibody to Perilipin 3 (PLIN3)
kl045Ra01 **素受体2(CNR2)多克隆抗体 Polyclonal Antibody to Cannabinoid Receptor 2, Macrophage (CNR2)
kl047Hu01 原钙黏素γA2(PCDHγA2)多克隆抗体 Polyclonal Antibody to Protocadherin Gamma A2 (PCDHgA2)
kl072Hu01 原钙黏素β16(PCDHβ16)多克隆抗体 Polyclonal Antibody to Protocadherin Beta 16 (PCDHb16)
kl095Hu01 原钙黏素15(PCDH15)多克隆抗体 Polyclonal Antibody to Protocadherin 15 (PCDH15)
kl095Mu01 原钙黏素15(PCDH15)多克隆抗体 Polyclonal Antibody to Protocadherin 15 (PCDH15)
kl107Hu01 肝配蛋白A1(EFNA1)多克隆抗体 Polyclonal Antibody to Ephrin A1 (EFNA1)
kl109Hu01 肝配蛋白A3(EFNA3)多克隆抗体 Polyclonal Antibody to Ephrin A3 (EFNA3)
kl110Hu01 肝配蛋白A4(EFNA4)多克隆抗体 Polyclonal Antibody to Ephrin A4 (EFNA4)
