产品详情
  • 产品名称:Anti-CBP抗体

  • 产品型号:CREB结合蛋白抗体
  • 产品厂商:KALANG
  • 产品文档:
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简单介绍:
Anti-CBP抗体产品质量稳定,实验效果明显,货期快,价格优惠,欢迎垂询订购!我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-CBP抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍:
Rabbit Anti-CBP
Cat. Number:
Anti-CBP抗体KL-1397R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
This gene is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein Anti-CBP抗体(CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. The protein encoded by this gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain. Mutations in this gene cause Rubinstein-Taybi syndrome (RTS). Chromosomal translocations involving this gene have been associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants encoding different isoforms. Anti-CBP抗体[provided by RefSeq, Feb 2009].
Also known as:
CREB-binding protein; CREBBP; GTF2D; TATA binding factor; TATA box factor; TATA sequence binding protein; TBP; TFIID; Transcription initiation factor TFIID TBP subunit; GTF2D1; MGC117320; MGC126054; MGC126055; Anti-CBP抗体SCA 17; SCA17; TATA binding factor; TATA box binding protein; TATA box factor; TATA sequence binding protein; TBP; TF2D; TFIID; Transcription initiation factor TFIID TBP subunit; CBP/p300; CREB binding protein; Cyclic AMP-responsive enhancer binding protein; RSTS; RTS; Rubinstein-Taybi syndrome.
Specificity:
Rabbit Polyclonal IgG, affinity purified by Protein A.
Reacts with: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, .
Immunogen: KLH conjugated synthetic peptide derived from human CBP.
Predicted Molecular Weight: 265kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 Anti-CBP抗体ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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