产品详情
简单介绍：
Anti-ARRB1/Beta-arrestin 1抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-ARRB1/Beta-arrestin 1抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-ARRB1/Beta-arrestin 1
Cat. Number:
Anti-ARRB1/Beta-arrestin 1抗体KL-20232R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Beta Arrestin 1 is a member of a family of proteins that are widely expressed but especially abundant in the central nervous system. Serving as an adaptor or scaffold molecule, beta Arrestin 1 is essential for mitogenic signaling.
Anti-ARRB1/Beta-arrestin 1抗体It mediates agonist dependent desensitization and internalization of G protein coupled receptors (GPCRs, e.g., beta 2 adrenergic receptor). After binding to their ligand and interacting with heterotrimeric G proteins, GPCRs are phosphorylated by G protein receptor kinases (GRKs) on serine residues. Beta Arrestin 1 has important roles in the cytoplasm and at the plasma membrane in the desensitization and internalization of G protein coupled receptors (GPCRs) and is increasingly appreciated to play an important role in the endocytosis and signaling of GPCRs. Beta Arrestin 1 in the cytosol is phosphorylated by ERK1 and 2 on serine 412 in a negative feedback mechanism and binds to the phosphorylated receptors at the plasma membrane. Serine 412 is then dephosphorylated and the GPCRs are internalized, leading to
Anti-ARRB1/Beta-arrestin 1抗体activation of the Ras, Raf, ERK1 and 2 signaling pathway.
Also known as:
Beta arrestin 1; ARB 1; ARB1; ARR 1; ARR1; ARRB 1; ARRB1; Arrestin beta 1; ARRB1_HUMAN; Arrestin 2; Arrestin beta-1; Beta-arrestin-1.
Anti-ARRB1/Beta-arrestin 1抗体
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, .
●
Immunogen: KLH conjugated synthetic peptide derived from human Beta-arrestin 1.
●
Predicted Molecular Weight: 47kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be Anti-ARRB1/Beta-arrestin 1抗体determined by the end user.
Not yet tested in other applications.
Optimal working dilutions must be Anti-ARRB1/Beta-arrestin 1抗体determined by the end user.
kl229Hu01 骨骼肌慢肌肌钙蛋白I(TNNI1)多克隆抗体 Polyclonal Antibody to Troponin I Type 1, Slow Skeletal (TNNI1)
kl229Ra01 骨骼肌慢肌肌钙蛋白I(TNNI1)多克隆抗体 Polyclonal Antibody to Troponin I Type 1, Slow Skeletal (TNNI1)
kl230Hu01 骨骼肌快肌肌钙蛋白I(TNNI2)多克隆抗体 Polyclonal Antibody to Troponin I Type 2, Fast Skeletal (TNNI2)
kl230Mu01 骨骼肌快肌肌钙蛋白I(TNNI2)多克隆抗体 Polyclonal Antibody to Troponin I Type 2, Fast Skeletal (TNNI2)
kl230Ra01 骨骼肌快肌肌钙蛋白I(TNNI2)多克隆抗体 Polyclonal Antibody to Troponin I Type 2, Fast Skeletal (TNNI2)
kl231Hu01 骨骼肌慢肌肌钙蛋白T(TNNT1)多克隆抗体 Polyclonal Antibody to Troponin T Type 1, Slow Skeletal (TNNT1)
kl232Hu01 心肌肌钙蛋白T(TNNT2)多克隆抗体 Polyclonal Antibody to Troponin T Type 2, Cardiac (TNNT2)
kl232Mu01 心肌肌钙蛋白T(TNNT2)多克隆抗体 Polyclonal Antibody to Troponin T Type 2, Cardiac (TNNT2)
kl232Ra01 心肌肌钙蛋白T(TNNT2)多克隆抗体 Polyclonal Antibody to Troponin T Type 2, Cardiac (TNNT2)
kl234Hu01 角蛋白6A(KRT6A)多克隆抗体 Polyclonal Antibody to Keratin 6A (KRT6A)
kl236Hu01 白三烯A4水解酶(LTA4H)多克隆抗体 Polyclonal Antibody to Leukotriene A4 Hydrolase (LTA4H)
kl236Mu01 白三烯A4水解酶(LTA4H)多克隆抗体 Polyclonal Antibody to Leukotriene A4 Hydrolase (LTA4H)
kl252Hu01 饥饿素/肥胖抑制素前**原(GHRL)多克隆抗体 Polyclonal Antibody to Ghrelin/Obestatin Preprohormone (GHRL)
kl263Hu01 细胞周期素A1(CCNA1)多克隆抗体 Polyclonal Antibody to Cyclin A1 (CCNA1)
kl264Hu01 细胞周期素B(CCNB)多克隆抗体 Polyclonal Antibody to Cyclin B (CCNB)
kl265Hu01 细胞周期素B2(CCNB2)多克隆抗体 Polyclonal Antibody to Cyclin B2 (CCNB2)
kl294Hu01 细胞色素P450家族成员1A2(CYP1A2)多克隆抗体 Polyclonal Antibody to Cytochrome P450 1A2 (CYP1A2)
kl294Ra01 细胞色素P450家族成员1A2(CYP1A2)多克隆抗体 Polyclonal Antibody to Cytochrome P450 1A2 (CYP1A2)
