产品详情
简单介绍：
Anti-phospho-Bid (Ser61)抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-phospho-Bid (Ser61)抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-phospho-Bid (Ser61)
Cat. Number:
Anti-phospho-Bid (Ser61)抗体KL-5231R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Bid, a BH3 domain
Anti-phospho-Bid (Ser61)抗体containing proapoptotic Bcl2 family member, is localized in the cytosolic fraction of cells as an inactive precursor. Its active form is generated upon proteolytic cleavage by caspase 8 in the Fas signaling pathway. Cleaved Bid translocates to mitochondria and releases its potent proapoptotic activity, which in turn induces cytochrome c release and mitochondrial damage. The cytochrome c releasing activity of Bid was antagonized by Bcl2. Mutation in the SH3 domain can diminish the cytochrome c releasing activity. In animal model studies, Bid deficient
Anti-phospho-Bid (Ser61)抗体mice are found resistant to the lethal effects of death factor signals relayed through Fas.
Also known as:
Bid (phospho S61); p-Bid (phospho S61); BH3 interacting domain death agonist; p22 BID; BID;) BH3-interacting domain death agonist; AltName: BH3-interacting domain death agonist p15; BH3-interacting domain death
Anti-phospho-Bid (Ser61)抗体agonist p13; p13 BID; BH3-interacting domain death agonist p11; p11 BID.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Mouse, .
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Immunogen: KLH conjugated Synthesised phosphopeptide derived from mouse Bid around the phosphorylation site of Ser61.
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Predicted Molecular Weight: 21kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500
Anti-phospho-Bid (Ser61)抗体ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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