产品详情
简单介绍：
Anti-Phospho-Bad (Ser134)抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-Phospho-Bad (Ser134)抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-Phospho-Bad (Ser134)
Cat. Number:
Anti-Phospho-Bad (Ser134)抗体KL-5217R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Bad is a member of the Bcl2 family and acts to promote apoptosis by forming heterodimers with the survival proteins Bcl2
Anti-Phospho-Bad (Ser134)抗体and BclxL, thus preventing them from binding with BAX. Bad is found on the outer mitochondrial membrane and, once phosphorylated in response to growth stimuli, translocates to the cytoplasm. The phosphorylation status of Bad represents a key checkpoint for death or cell survival. JNK-induced phosphorylation of BAD serine 128 promotes the apoptotic role of Bad by opposing the inhibitory effect of growth factor on Bad-mediated apoptosis. Cdc2-induced phosphorylation of Bad serine 128 has an inhibitory effect on its interaction with 14-3-3 proteins. The latter interaction is critical for Bad phosphorylation at serine 155, a site within the BH3 domain that leads to the release of BclxL and the promotion of cell survival. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
Also known as:
Bad (phospho S134);
Anti-Phospho-Bad (Ser134)抗体Bad (phospho Ser134); p-Bad (S134);p- Bad (Ser134); p-Bad (phospho Ser134); BBC 2; BBC2; BBC6; Bcl 2 Antagonist of Cell Death; Bcl 2 Binding Component 6; BCL X / BCL 2 Binding Protein; BCL X Binding Protein; Bcl XL/Bcl 2 Associated Death Promoter; Bcl-2-like protein 8; Bcl2 antagonist of cell death; BCL2 antagonist of cell death protein; BCL2 associated agonist of cell death; Bcl2 Associated Death Promoter; BCL2 binding component 6; BCL2 binding protein; Bcl2 Like 8 Protein; Bcl2-L-8; BCL2L8; BclXL; Proapoptotic BH3 Only Protein; BAD_HUMAN; Bcl-2-binding component 6.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, .
●
Immunogen: KLH
Anti-Phospho-Bad (Ser134)抗体conjugated Synthesised phosphopeptide derived from human BAD around the phosphorylation site of Ser134.
●
Predicted Molecular Weight: 18kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working Anti-Phospho-Bad (Ser134)抗体dilutions must be determined by the end user.
Not yet tested in other applications.
Optimal working Anti-Phospho-Bad (Ser134)抗体dilutions must be determined by the end user.
kl267Rb51 组织蛋白酶K(CTSK)多克隆抗体 Polyclonal Antibody to Cathepsin K (CTSK)
kl267Si01 组织蛋白酶K(CTSK)多克隆抗体 Polyclonal Antibody to Cathepsin K (CTSK)
kl269Hu01 磷酯酶Cγ1(PLCγ1)多克隆抗体 Polyclonal Antibody to Phospholikle C Gamma 1 (PLCg1)
kl270Hu01 T-细胞激活连接蛋白(LAT)多克隆抗体 Polyclonal Antibody to Linker For Activation Of T-Cell (LAT)
kl270Mu01 T-细胞激活连接蛋白(LAT)多克隆抗体 Polyclonal Antibody to Linker For Activation Of T-Cell (LAT)
kl270Ra01 T-细胞激活连接蛋白(LAT)多克隆抗体 Polyclonal Antibody to Linker For Activation Of T-Cell (LAT)
kl272Bo01 转运蛋白1(TNPO1)多克隆抗体 Polyclonal Antibody to Transportin 1 (TNPO1)
kl272Hu01 转运蛋白1(TNPO1)多克隆抗体 Polyclonal Antibody to Transportin 1 (TNPO1)
kl272Mu01 转运蛋白1(TNPO1)多克隆抗体 Polyclonal Antibody to Transportin 1 (TNPO1)
kl273Hu01 抑制素结合蛋白(INHBP)多克隆抗体 Polyclonal Antibody to Inhibin Binding Protein (INHBP)
kl273Mu01 抑制素结合蛋白(INHBP)多克隆抗体 Polyclonal Antibody to Inhibin Binding Protein (INHBP)
kl273Ra01 抑制素结合蛋白(INHBP)多克隆抗体 Polyclonal Antibody to Inhibin Binding Protein (INHBP)
kl274Bo01 胰岛素样生长因子结合蛋白6(IGFBP6)多克隆抗体 Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 6 (IGFBP6)
kl274Cp01 胰岛素样生长因子结合蛋白6(IGFBP6)多克隆抗体 Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 6 (IGFBP6)
kl274Eq01 胰岛素样生长因子结合蛋白6(IGFBP6)多克隆抗体 Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 6 (IGFBP6)
kl274Hu01 胰岛素样生长因子结合蛋白6(IGFBP6)多克隆抗体 Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 6 (IGFBP6)
kl274Mu01 胰岛素样生长因子结合蛋白6(IGFBP6)多克隆抗体 Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 6 (IGFBP6)
