产品详情
简单介绍：
Anti-phospho-ARP3 (Ser418)抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-phospho-ARP3 (Ser418)抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-phospho-ARP3 (Ser418)
Cat. Number:
Anti-phospho-ARP3 (Ser418)抗体KL-8999R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M
Anti-phospho-ARP3 (Ser418)抗体TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Actin polymerization is required for a variety of cell functions, including chemotaxis, cell migration, cell adhesion, and platelet activation. Cells trigger actin polymerization through either the de novo nucleation of filaments from monomeric actin, the severing of existing filaments to create uncapped barbed ends, or the
Anti-phospho-ARP3 (Ser418)抗体uncapping existing barbed ends. The nucleation of actin is a rate-limiting and unfavorable reaction in actin polymerization and therefore requires the involvement of the Arp2/3 complex, which helps create new filaments and promotes the end-to-side cross-linking of actin filaments into the branching meshwork. The Arp2/3 complex consists of the actin-related proteins Arp2 and Arp3, and various other accessory proteins. The Arp2/3 complex promotes actin nucleation by binding the pointed end of actin filaments, or by associating with the side of an existing filament, and nucleates growth in the barbed direction. In addition, the Arp2/3 complex also mediates actin cytoskeletal outgrowths that are regulated by the Rho family of small GTPases. In response to GTP-binding Cdc42, the Arp2/3 complex binds the Cdc42 substrates,
Anti-phospho-ARP3 (Ser418)抗体namely the WASP proteins, and initiates the formation of lamellipodia and filopodia.
Also known as:
ARP3 (phospho-Ser418); ARP3 (phospho S418); Actin-like protein 3; Actin-related protein 3; ACTR3; ARP3
Anti-phospho-ARP3 (Ser418)抗体actin-related protein 3 homolog; ARP3_HUMAN.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, .
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Immunogen: KLH conjugated synthetic peptide derived from human phospho-ARP3 (Ser418).
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Predicted Molecular Weight: 47kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working Anti-phospho-ARP3 (Ser418)抗体dilutions must be determined by the end user.
Not yet tested in other applications.
Optimal working Anti-phospho-ARP3 (Ser418)抗体dilutions must be determined by the end user.
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