产品详情
简单介绍：
Anti-phospho-AMPK alpha 2 (Ser491)抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-phospho-AMPK alpha 2 (Ser491)抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-phospho-AMPK alpha 2 (Ser491)
Cat. Number:
Anti-phospho-AMPK alpha 2 (Ser491)抗体KL-12469R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer
Anti-phospho-AMPK alpha 2 (Ser491)抗体consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008]
Also known as:
Anti-phospho-AMPK alpha 2 (Ser491)抗体AMPK alpha 2 (phospho S491); AMPK alpha 2 (phospho Ser491); p-AMPK alpha 2 (Ser491); p-AMPK alpha 2 (S491); p-AMPK2(phospho S491); 5'-AMP-activated protein kinase catalytic subunit alpha-2; AAPK2_HUMAN; AMP activated protein kinase alpha 2 catalytic subunit; AMPK 2; AMPK alpha 2 chain; AMPK subunit alpha-2; ; AMPKalpha2; PRKAA 2; PRKAA; PRKAA2; Protein kinase AMP activated alpha 2 catalytic subunit.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, .
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Immunogen: KLH conjugated synthesised phosphopeptide derived from human AMPK alpha 2 around the
Anti-phospho-AMPK alpha 2 (Ser491)抗体phosphorylation site of Ser491.
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Predicted Molecular Weight: 62kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Anti-phospho-AMPK alpha 2 (Ser491)抗体Optimal working dilutions must be determined by the end user.
Not yet tested in other applications.
Anti-phospho-AMPK alpha 2 (Ser491)抗体Optimal working dilutions must be determined by the end user.
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