产品详情
简单介绍：
Anti-AKR1C3抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-AKR1C3抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-AKR1C3
Cat. Number:
Anti-AKR1C3抗体KL-11401R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
DD3 is a unique enzyme that can specifically catalyze the dehydrogenation of trans-benzenedihydrodiol and trans-naphthalenedihydrodiol. Human liver contains isoforms of dihydrodiol dehydrogenase (DD1, DD2, DD3 and DD4), which belong to the aldo-oxo reductase/aldo-keto reductase (AKR)
Anti-AKR1C3抗体superfamily, have 20Alpha- or 3Alpha-hydroxysteroid dehydrogenase (HSD) activity. DD1 is also designated AKR1C1, DDH or DDH1 while DD2 also can be designated AKR1C2, dDD, BABP or DDH2. AKR1C3 and 3Alpha-HSD are alternate designations for DD3, while DD4 also can be called AKR1C4, CD or CHDR. DD1 and DD2 are 20Alpha-HSDs, whereas DD3 and DD4 are the 3Alpha-HSDs. The multiple human cytosolic dihydrodiol dehydrogenases are involved in the metabolism of xenobiotics, such as polycyclic aromatic hydrocarbons, pesticides and steroid hormones, and are responsible for the reduction of ketone-containing drugs by using NADH or NADPH as a cofactor. The 20Alpha-HSD catalyzes the reaction of progesterone to the inactive form 20Alpha-hydroxyprogesterone. The 3Alpha-HSD is a cytosolic, monomeric, NADPH-dependent oxidoreductase that reduces 3-keto-5-dihydrosteroids to their tetrahydro products.
Anti-AKR1C3抗体DD1 and DD2 are ubiquitously expressed, whereas DD4 mRNA is restricted to the liver.
Also known as:
17 beta HSD 5; 17
Anti-AKR1C3抗体beta hydroxysteroid dehydrogenase type 5; 17-beta-HSD 5; 17-beta-hydroxysteroid dehydrogenase type 5; 2-dihydrobenzene-1; 2-diol dehydrogenase; 3 alpha hydroxysteroid dehydrogenase type II; 3-alpha-HSD type 2; 3-alpha-HSD type II; 3-alpha-HSD type II, brain; 3-alpha-hydroxysteroid dehydrogenase type 2; AK1C3_HUMAN; AKR1 C3; AKR1C3; Aldo keto reductase family 1 member C3; Aldo-keto reductase family 1 member C3; brain; Chlordecone reductase; Chlordecone reductase homolog HAKRb; DD-3; DD3; DDH1; DDX; Dihydrodiol dehydrogenase 3; Dihydrodiol dehydrogenase type I; Dihydrodiol dehydrogenase X; HA1753; HAKRB; HAKRe; hluPGFS; HSD17B5; Indanol dehydrogenase; KIAA0119; PGFS; Prostaglandin F synthase; Testosterone 17-beta-dehydrogenase 5; Trans-1; Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; Type IIb 3 alpha hydroxysteroid dehydrogenase.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Dog, Pig, Cow, Horse, Rabbit, .
●
Immunogen: KLH conjugated synthetic peptide derived from human AKR1C3.
●
Predicted Molecular
Anti-AKR1C3抗体Weight: 36kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
kl350Ra01 Ⅰ型胶原α1(COL1α1)多克隆抗体 Polyclonal Antibody to Collagen Type I Alpha 1 (COL1a1)
kl357Hu01 成纤维细胞生长因子5(FGF5)多克隆抗体 Polyclonal Antibody to Fibroblast Growth Factor 5 (FGF5)
kl362Hu01 尾加压素2(UST2)多克隆抗体 Polyclonal Antibody to Urotensin 2 (UST2)
kl363Hu01 血小板内皮细胞粘附分子1(PECAM1)多克隆抗体 Polyclonal Antibody to Platelet/Endothelial Cell Adhesion Molecule (PECAM1)
kl363Mu01 血小板内皮细胞粘附分子1(PECAM1)多克隆抗体 Polyclonal Antibody to Platelet/Endothelial Cell Adhesion Molecule (PECAM1)
kl363Ra01 血小板内皮细胞粘附分子1(PECAM1)多克隆抗体 Polyclonal Antibody to Platelet/Endothelial Cell Adhesion Molecule (PECAM1)
kl370Hu01 β-血小板球蛋白(βTG)多克隆抗体 Polyclonal Antibody to Beta-Thromboglobulin (bTG)
kl370Mu01 β-血小板球蛋白(βTG)多克隆抗体 Polyclonal Antibody to Beta-Thromboglobulin (bTG)
kl370Ra01 β-血小板球蛋白(βTG)多克隆抗体 Polyclonal Antibody to Beta-Thromboglobulin (bTG)
kl371Bo01 10kDa干扰素γ诱导蛋白(IP10)多克隆抗体 Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10)
kl371Ca01 10kDa干扰素γ诱导蛋白(IP10)多克隆抗体 Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10)
kl371Hu01 10kDa干扰素γ诱导蛋白(IP10)多克隆抗体 Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10)
kl371Mu01 10kDa干扰素γ诱导蛋白(IP10)多克隆抗体 Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10)
kl371Ra01 10kDa干扰素γ诱导蛋白(IP10)多克隆抗体 Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10)
