产品详情
简单介绍：
Anti-ATG18抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-ATG18抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-ATG18
Cat. Number:
Anti-ATG18抗体XY-3871R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Members of the
Anti-ATG18抗体WIPI subfamily of WD40 repeat proteins, such as WIPI1 (WD repeat domain, phosphoinositide interacting 1), have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids. WIPI1 moved through the same set of endosomal membranes as that followed by mannose-6-phosphate receptor (MPR). Consistent with this, WIPI1 was enriched in clathrin-coated vesicles. Overexpression of WIPI1 disrupted the function of the MPR pathway, whereas expression of a double point mutant unable to bind phosphoinositides had no effect. Suppression
Anti-ATG18抗体of WIPI1 by interfering RNA indicated that WIPI1 is required for normal endosomal organization and distribution of IGF2R.
Also known as:
ATG 18; ATG18;
Anti-ATG18抗体Atg18 protein homolog; ATG18A; WD repeat domain phosphoinositide interacting 1; WD repeat domain phosphoinositide interacting protein 1; WD40 repeat protein interacting with phosphoInositides of 49kDa; WIPI 1 alpha; WIPI 1; WIPI 49; WIPI 49 kDa ; WIPI49.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Pig, .
●
Immunogen: KLH conjugated synthetic peptide derived from mouse WIPI1.
●
Predicted Molecular
Anti-ATG18抗体Weight: 49kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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