产品详情
  • 产品名称:Anti-Factor alpha XIIa抗体

  • 产品型号:凝固第XII因子/抗血友病因子抗体
  • 产品厂商:KALANG
  • 产品文档:
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简单介绍:
Anti-Factor alpha XIIa抗体产品质量稳定,实验效果明显,货期快,价格优惠,欢迎垂询订购!我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-Factor alpha XIIa抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍:
Rabbit Anti-Factor alpha XIIa
Cat. Number:
Anti-Factor alpha XIIa抗体KL-14681R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
This gene encodes coagulation factor XII which circulates in blood as a zymogen. This single chain zymogen is converted to a two-chain Anti-Factor alpha XIIa抗体serine protease with an heavy chain (alpha-factor XIIa) and a light chain. The heavy chain contains two fibronectin-type domains, two epidermal growth factor (EGF)-like domains, a kringle domain and a proline-rich domain, whereas the light chain contains only a catalytic domain. On activation, further cleavages takes place in the heavy chain, resulting in the production of beta-factor XIIa light chain and the alpha-factor XIIa light chain becomes beta-factor XIIa heavy chain. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then to beta-factor XIIa. The active factor XIIa participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. It activates coagulation factors VII and XI. Defects in this gene do not cause any clinical symptoms and the sole effect is that whole-blood clotting time is prolonged. [provided by RefSeq, Jul 2008]
Also known as:
Coagulation factor XII; coagulation factor Anti-Factor alpha XIIa抗体XIIa heavy chain; Coagulation factor XIIa light chain; F12; FA12_HUMAN; Factor XII; HAE3; HAEX; HAF; Hageman factor.
Specificity:
Rabbit Polyclonal IgG, affinity purified by Protein A.
Reacts with: Human, Mouse, Rat, Dog, Cow, Horse, Sheep, .
Immunogen: KLH conjugated synthetic peptide derived from human Factor a.
Predicted Molecular Weight: Anti-Factor alpha XIIa抗体66kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-Factor alpha XIIa抗体
Optimal working dilutions must be determined by the end user.
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