产品详情
简单介绍：
Anti-Claudin 14抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-Claudin 14抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-Claudin 14
Cat. Number:
Anti-Claudin 14抗体KL-5025R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The Claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial
Anti-Claudin 14抗体and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the claudins, Occludin and Junction adhesion molecules. Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions. Claudin-14 is a multi-pass membrane protein that is expressed in liver, kidney and ear. Defects in the gene encoding claudin-14 are the cause of non-syndromic sensorineural deafness autosomal recessive type 29 (DFNB29), a form of hearing loss resulting from damage to either nerve pathways or neural receptors of the inner ear.
Also known as:
Claudin-14; CLDN14;
Anti-Claudin 14抗体DFNB29; Human CLDN14 gene; OTTHUMP00000109046; OTTHUMP00000109049; OTTMUSP00000021531; UNQ777/PRO1571.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Guinea Pig, .
●
Immunogen: KLH conjugated synthetic peptide derived from human Claudin 14.
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Predicted Molecular Weight: 26kDa.
Storage:
Shipped at 4℃, Store at -20℃
Anti-Claudin 14抗体(Avoid repeated freeze/thaw cycles).
Application:
IHC-P=1:100-500 IHC-F=1:100-500
Not yet tested in other applications.
Optimal working dilutions Anti-Claudin 14抗体must be determined by the end user.
Not yet tested in other applications.
Optimal working dilutions Anti-Claudin 14抗体must be determined by the end user.
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