产品详情
简单介绍：
Anti-Caspase-3抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-Caspase-3抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-Caspase-3
Cat. Number:
Anti-Caspase-3抗体KL-0081R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The caspase family of cysteine proteases play a key role in apoptosis. Caspase 3 is the most extensively studied apoptotic protein among caspase family members. Caspase 3 is synthesized as inactive pro enzyme that is processed in cells undergoing apoptosis by self proteolysis and/or cleavage by other
Anti-Caspase-3抗体upstream proteases (e.g. Caspases 8, 9 and 10). The processed form of Caspase 3 consists of large (17kDa) and small (12kDa) subunits which associate to form an active enzyme. Caspase 3 is cleaved at Asp28 Ser29 and Asp175 Ser176. The active Caspase 3 proteolytically cleaves and activates other caspases (e.g. Caspases 6, 7 and 9), as well as relevant targets in the cells (e.g. PARP and DFF). Alternative splicing of this gene results in two transcript variants which encode the same protein. In immunohistochemical studies Caspase 3 expression has been shown to be widespread but not present in all cell types (e.g. commonly reported in epithelial cells of skin, renal proximal tubules and collecting ducts). Differences in the level of Caspase 3 have been reported in cells of short lived nature (eg germinal centre B cells) and those that are long lived (eg mantle zone B cells). Caspase 3 is the predominant caspase involved in the cleavage of amyloid beta
Anti-Caspase-3抗体4A precursor protein, which is associated with neuronal death in Alzheimer's disease.
Reacts with Caspase-3 subunit p17 and precursor.
Reacts with Caspase-3 subunit p17 and precursor.
Also known as:
Caspase-3 subunit p17; APOPAIN; CASP3; Caspase 3 apoptosis related cysteine protease; Caspase3; CPP32; CPP32B; Cysteine protease CPP32; Human cysteine protease CPP32 isoform alpha mRNA complete cds; PARP cleavage protease; SCA 1; SCA1; SREBP cleavage activity 1; Yama; CASP3_HUMAN;
Anti-Caspase-3抗体Caspase-3; CASP-3; Apopain; Protein Yama; SREBP cleavage activity 1; SCA-1.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, .
●
Immunogen: KLH conjugated synthetic peptide derived from human caspase-3 p17 subunit.
●
Predicted Molecular Weight: 28kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500
Anti-Caspase-3抗体ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:50-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
kl592Hu01 生长抑素(SST)多克隆抗体 Polyclonal Antibody to Somatostatin (SST)
kl592Mu01 生长抑素(SST)多克隆抗体 Polyclonal Antibody to Somatostatin (SST)
kl592Ra01 生长抑素(SST)多克隆抗体 Polyclonal Antibody to Somatostatin (SST)
kl592Po01 生长抑素(SST)多克隆抗体 Polyclonal Antibody to Somatostatin (SST)
kl100Hu01 突触核蛋白(SNC)多克隆抗体 Polyclonal Antibody to Synuclein (SNC)
kl458Ge01 睾酮(Testo)多克隆抗体 Polyclonal Antibody to Testosterone (Testo)
kl839Hu01 促甲状腺素释放**(TRH)多克隆抗体 Polyclonal Antibody to Thyrotropin Releasing Hormone (TRH)
kl839Mu01 促甲状腺素释放**(TRH)多克隆抗体 Polyclonal Antibody to Thyrotropin Releasing Hormone (TRH)
kl839Ra01 促甲状腺素释放**(TRH)多克隆抗体 Polyclonal Antibody to Thyrotropin Releasing Hormone (TRH)
kl839Po01 促甲状腺素释放**(TRH)多克隆抗体 Polyclonal Antibody to Thyrotropin Releasing Hormone (TRH)
kl133Hu01 肿瘤坏死因子α(TNFα)多克隆抗体 Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa)
kl133Mu01 肿瘤坏死因子α(TNFα)多克隆抗体 Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa)
kl133Ra01 肿瘤坏死因子α(TNFα)多克隆抗体 Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa)
kl133Gu01 肿瘤坏死因子α(TNFα)多克隆抗体 Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa)
kl133Rb52 肿瘤坏死因子α(TNFα)多克隆抗体 Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa)
kl133Si01 肿瘤坏死因子α(TNFα)多克隆抗体 Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa)
kl133Ca01 肿瘤坏死因子α(TNFα)多克隆抗体 Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa)
kl133Po01 肿瘤坏死因子α(TNFα)多克隆抗体 Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa)
kl133Bo01 肿瘤坏死因子α(TNFα)多克隆抗体 Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa)
kl133Cp01 肿瘤坏死因子α(TNFα)多克隆抗体 Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa)
