产品详情
简单介绍：
Anti-Bacillus anthracis lethal factor抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-Bacillus anthracis lethal factor抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-Bacillus anthracis lethal factor
Cat. Number:
Anti-Bacillus anthracis lethal factor抗体KL-12564R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The protease enzyme Lethal Factor (LF) is one of the three proteins (LF, EF & PA) composing the anthrax toxin produced by Bacillus anthracis, a bacteria which can infect many mammalian species and that may be fatal. LF is not toxic by itself, but when associated with Protective Antigen (PA), can then gain entry to cells. Once inside the cell, LF then cleaves the N terminal of most dual specificity mitogen activated protein
Anti-Bacillus anthracis lethal factor抗体kinase kinases (MAPKKs or MAP2Ks) (except for MAP2K5). Cleavage invariably occurs within the N terminal proline rich region preceding the kinase domain, thus disrupting a sequence involved in directing specific protein protein interactions necessary for the assembly of signaling complexes. There may be other cytosolic targets of LF involved in cytotoxicity. The proteasome may mediate a toxic process initiated by LF in the cell cytosol involving degradation of unidentified molecules that are essential for macrophage homeostasis. This is an early step in LF intoxication, but it is downstream of the cleavage by LF of MEK1 or other putative substrates.
Also known as:
Anthrax lethal factor; Anthrax lethal
Anti-Bacillus anthracis lethal factor抗体toxin endopeptidase component; Anthrax LF; bacillus anthracis lethal factor; Lef; LF; LEF_BACAN.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Anthrax LF (Lethal Factor) produced by Bacillus anthracis.
●
Immunogen: KLH conjugated synthetic peptide derived from Bacillus anthracis lethal factor.
●
Predicted Molecular Weight: 90kDa.
Storage:
Shipped at 4℃, Store at -20℃
Anti-Bacillus anthracis lethal factor抗体(Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be Anti-Bacillus anthracis lethal factor抗体determined by the end user.
Not yet tested in other applications.
Optimal working dilutions must be Anti-Bacillus anthracis lethal factor抗体determined by the end user.
kl938Ra01 足突蛋白(PDCN)多克隆抗体 Polyclonal Antibody to Podocin (PDCN)
kl940Hu01 趋化因子C-X-C-基元受体4(CXCR4)多克隆抗体 Polyclonal Antibody to Chemokine C-X-C-Motif Receptor 4 (CXCR4)
kl940Mu01 趋化因子C-X-C-基元受体4(CXCR4)多克隆抗体 Polyclonal Antibody to Chemokine C-X-C-Motif Receptor 4 (CXCR4)
kl940Po01 趋化因子C-X-C-基元受体4(CXCR4)多克隆抗体 Polyclonal Antibody to Chemokine C-X-C-Motif Receptor 4 (CXCR4)
kl944Hu01 岩藻糖基转移酶3(FUT3)多克隆抗体 Polyclonal Antibody to Fucosyltransferase 3 (FUT3)
kl945Hu01 趋化素(CHEM)多克隆抗体 Polyclonal Antibody to Chemerin (CHEM)
kl945Ra01 趋化素(CHEM)多克隆抗体 Polyclonal Antibody to Chemerin (CHEM)
kl948Hu01 胸腺嘧啶核苷磷酸化酶(TP)多克隆抗体 Polyclonal Antibody to Thymidine Phosphorylase (TP)
kl948Mu01 胸腺嘧啶核苷磷酸化酶(TP)多克隆抗体 Polyclonal Antibody to Thymidine Phosphorylase (TP)
kl950Hu01 血管性血友病因子裂解蛋白酶(vWFCP)多克隆抗体 Polyclonal Antibody to Von Willebrand Factor Cleaving Protease (vWFCP)
kl959Hu01 L1-细胞粘附分子(L1CAM)多克隆抗体 Polyclonal Antibody to L1-Cell Adhesion Molecule (L1CAM)
kl959Mu01 L1-细胞粘附分子(L1CAM)多克隆抗体 Polyclonal Antibody to L1-Cell Adhesion Molecule (L1CAM)
kl960Hu01 ATP结合盒转运蛋白G2(ABCG2)多克隆抗体 Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2)
kl960Mu01 ATP结合盒转运蛋白G2(ABCG2)多克隆抗体 Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2)
kl965Hu01 α2-巨球蛋白样蛋白1(α2ML1)多克隆抗体 Polyclonal Antibody to Alpha-2-Macroglobulin Like Protein 1 (a2ML1)
kl966Hu01 唾液酸结合Ig样凝集素1(SIGLEC1)多克隆抗体 Polyclonal Antibody to Sialic Acid Binding Ig Like Lectin 1 (SIGLEC1)
kl971Hu01 磷脂酰肌醇蛋白聚糖3(GPC3)多克隆抗体 Polyclonal Antibody to Glypican 3 (GPC3)
kl973Hu01 血管紧张素Ⅱ受体2(AGTR2)多克隆抗体 Polyclonal Antibody to Angiotensin II Receptor 2 (AGTR2)
kl976Hu01 维甲酸受体α(RARα)多克隆抗体 Polyclonal Antibody to Retinoic Acid Receptor Alpha (RARa)
kl976Ra01 维甲酸受体α(RARα)多克隆抗体 Polyclonal Antibody to Retinoic Acid Receptor Alpha (RARa)
kl977Mu01 盘状结构域受体家族成员1(DDR1)多克隆抗体 Polyclonal Antibody to Discoidin Domain Receptor Family, Member 1 (DDR1)
kl979Hu01 亲环素A(CYPA)多克隆抗体 Polyclonal Antibody to Cyclophilin A (CYPA)
kl979Mu01 亲环素A(CYPA)多克隆抗体 Polyclonal Antibody to Cyclophilin A (CYPA)
kl979Ra01 亲环素A(CYPA)多克隆抗体 Polyclonal Antibody to Cyclophilin A (CYPA)
