产品详情
简单介绍：
Anti-phospho-B-Raf (Ser446)抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-phospho-B-Raf (Ser446)抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-phospho-B-Raf (Ser446)
Cat. Number:
Anti-phospho-B-Raf (Ser446)抗体KL-5232R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The Raf kinases are important intermediates in signal transduction. Raf protein family members, including A Raf and
Anti-phospho-B-Raf (Ser446)抗体B Raf, have intrinsic serine/threonine kinase activity. Interaction between Ras proteins and Raf proteins results in Raf-mediated phosphorylation and activation of MEK (also known as MAP kinase kinase). Defects in BRAF are involved in a wide range of cancers. B-Raf is a serine/threonine protein kinase that acts as a signal transducer from membrane-associated receptors to nuclear transcription factors. 1 BRAF is important for the regulation of cell proliferation and determination of cell fate during embryogenesis. BRAF acts downstream of Ras and upstream of MEK in the Ras-Raf-MEK-ERK signal transduction pathway, which is a conserved RAS-activated protein kinase cascade that regulates cell growth, proliferation, and differentiation in response to growth factors, cytokines, and hormones.
Also known as:
B Raf (phospho S446);
Anti-phospho-B-Raf (Ser446)抗体p-B Raf (phospho S446); 94 kDa B raf protein; B raf 1; B Raf proto oncogene serine threonine protein kinase; BRAF 1; Braf; BRAF1; cRmil; MGC126806; MGC138284; Murine sarcoma viral (v-raf) oncogene homolog B1; Murine sarcoma viral v raf oncogene homolog B1; p94; RAFB 1; RAFB1; v raf murine sarcoma viral oncogene homolog B1; FLJ95109.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, .
●
Immunogen: KLH conjugated Synthesised phosphopeptide derived from human B-Raf around the phosphorylation site of Ser446.
●
Predicted Molecular Weight: 94kDa.
Storage:
Shipped at 4℃, Store
Anti-phospho-B-Raf (Ser446)抗体at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be Anti-phospho-B-Raf (Ser446)抗体determined by the end user.
Not yet tested in other applications.
Optimal working dilutions must be Anti-phospho-B-Raf (Ser446)抗体determined by the end user.
kl323Hu01 不均一核糖核蛋白A2/B1(HNRPA2B1)多克隆抗体 Polyclonal Antibody to Heterogeneous Nuclear Ribonucleoprotein A2/B1 (HNRPA2B1)
kl329Hu01 多功能肽酶2(LMP2)多克隆抗体 Polyclonal Antibody to Large Multifunctional Peptidase 2 (LMP2)
kl335Ra01 尾加压素2受体(UTS2R)多克隆抗体 Polyclonal Antibody to Urotensin 2 Receptor (UTS2R)
kl338Mu01 微管关联蛋白1A(MAP1A)多克隆抗体 Polyclonal Antibody to Microtubule Associated Protein 1A (MAP1A)
kl340Hu01 蛛**受体3(LPHN3)多克隆抗体 Polyclonal Antibody to Latrophilin 3 (LPHN3)
kl344Hu01 回肠脂肪酸结合蛋白(FABP6)多克隆抗体 Polyclonal Antibody to Fatty Acid Binding Protein 6, Ileal (FABP6)
kl344Mu01 回肠脂肪酸结合蛋白(FABP6)多克隆抗体 Polyclonal Antibody to Fatty Acid Binding Protein 6, Ileal (FABP6)
kl347Hu01 着丝粒蛋白F(CENPF)多克隆抗体 Polyclonal Antibody to Centromere Protein F (CENPF)
kl350Mu01 Ⅰ型胶原α1(COL1α1)多克隆抗体 Polyclonal Antibody to Collagen Type I Alpha 1 (COL1a1)
kl350Ra01 Ⅰ型胶原α1(COL1α1)多克隆抗体 Polyclonal Antibody to Collagen Type I Alpha 1 (COL1a1)
kl357Hu01 成纤维细胞生长因子5(FGF5)多克隆抗体 Polyclonal Antibody to Fibroblast Growth Factor 5 (FGF5)
kl362Hu01 尾加压素2(UST2)多克隆抗体 Polyclonal Antibody to Urotensin 2 (UST2)
kl363Hu01 血小板内皮细胞粘附分子1(PECAM1)多克隆抗体 Polyclonal Antibody to Platelet/Endothelial Cell Adhesion Molecule (PECAM1)
kl363Mu01 血小板内皮细胞粘附分子1(PECAM1)多克隆抗体 Polyclonal Antibody to Platelet/Endothelial Cell Adhesion Molecule (PECAM1)
kl363Ra01 血小板内皮细胞粘附分子1(PECAM1)多克隆抗体 Polyclonal Antibody to Platelet/Endothelial Cell Adhesion Molecule (PECAM1)
kl370Hu01 β-血小板球蛋白(βTG)多克隆抗体 Polyclonal Antibody to Beta-Thromboglobulin (bTG)
kl370Mu01 β-血小板球蛋白(βTG)多克隆抗体 Polyclonal Antibody to Beta-Thromboglobulin (bTG)
kl370Ra01 β-血小板球蛋白(βTG)多克隆抗体 Polyclonal Antibody to Beta-Thromboglobulin (bTG)
kl371Bo01 10kDa干扰素γ诱导蛋白(IP10)多克隆抗体 Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10)
kl371Ca01 10kDa干扰素γ诱导蛋白(IP10)多克隆抗体 Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10)
kl371Hu01 10kDa干扰素γ诱导蛋白(IP10)多克隆抗体 Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10)
kl371Mu01 10kDa干扰素γ诱导蛋白(IP10)多克隆抗体 Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10)
