产品详情
简单介绍：
Anti-AICDA抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-AICDA抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-AICDA
Cat. Number:
Anti-AICDA抗体KL-7855R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
RNA-editing deaminase
Anti-AICDA抗体involved in somatic hypermutation, gene conversion, and class-switch recombination. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses.
Tissue specificity:Strongly expressed in lymph nodes and tonsils.
Involvement in disease:Defects in AICDA are the cause of hyper-IgM immunodeficiency syndrome type 2 (HIGM2); also Anti-AICDA抗体known as hyper-IgM syndrome 2. HIGM2 is an autosomal recessive disorder characterized by normal or elevated serum IgM levels with absence of IgG, IgA, and IgE, resulting in a profound susceptibility to bacterial infections. HIGM2 causes the absence of Ig class switch recombination (CSR), the lack of Ig somatic hypermutations, and lymph node hyperplasia caused by the presence of giant germinal centers.
Tissue specificity:Strongly expressed in lymph nodes and tonsils.
Involvement in disease:Defects in AICDA are the cause of hyper-IgM immunodeficiency syndrome type 2 (HIGM2); also Anti-AICDA抗体known as hyper-IgM syndrome 2. HIGM2 is an autosomal recessive disorder characterized by normal or elevated serum IgM levels with absence of IgG, IgA, and IgE, resulting in a profound susceptibility to bacterial infections. HIGM2 causes the absence of Ig class switch recombination (CSR), the lack of Ig somatic hypermutations, and lymph node hyperplasia caused by the presence of giant germinal centers.
Also known as:
Activation induced
Anti-AICDA抗体cytidine deaminase; Activation induced deaminase; Activation-induced cytidine deaminase; AICDA; AICDA_HUMAN; AID; ARP 2; ARP2; CDA 2; CDA2; Cytidine aminohydrolase; HIGM2; Integrated into Burkitt's lymphoma cell line Ramos.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Cow, Horse, Rabbit, .
●
Immunogen: KLH conjugated synthetic peptide derived from human AICDA.
●
Predicted Molecular Weight: 24kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working Anti-AICDA抗体dilutions must be determined by the end user.
Not yet tested in other applications.
Optimal working Anti-AICDA抗体dilutions must be determined by the end user.
kl764Hu01 叉头框蛋白O1(FOXO1)多克隆抗体 Polyclonal Antibody to Forkhead Box Protein O1 (FOXO1)
kl766Hu01 解整合素金属蛋白酶10(ADAM10)多克隆抗体 Polyclonal Antibody to A Disintegrin And Metalloprotease 10 (ADAM10)
kl766Ra01 解整合素金属蛋白酶10(ADAM10)多克隆抗体 Polyclonal Antibody to A Disintegrin And Metalloprotease 10 (ADAM10)
kl768Hu01 足盂蛋白(PCX)多克隆抗体 Polyclonal Antibody to Podocalyxin (PCX)
kl768Mu01 足盂蛋白(PCX)多克隆抗体 Polyclonal Antibody to Podocalyxin (PCX)
kl770Hu01 胱天蛋白酶5(CASP5)多克隆抗体 Polyclonal Antibody to Caskle 5 (CASP5)
kl771Hu01 趋化因子C-X-C-基元配体16(CXCL16)多克隆抗体 Polyclonal Antibody to Chemokine C-X-C-Motif Ligand 16 (CXCL16)
kl771Ra01 趋化因子C-X-C-基元配体16(CXCL16)多克隆抗体 Polyclonal Antibody to Chemokine C-X-C-Motif Ligand 16 (CXCL16)
kl775Hu01 己糖激酶1(HK1)多克隆抗体 Polyclonal Antibody to Hexokinase 1 (HK1)
kl775Mu01 己糖激酶1(HK1)多克隆抗体 Polyclonal Antibody to Hexokinase 1 (HK1)
kl776Hu01 丙酮酸脱氢酶α(PDHα)多克隆抗体 Polyclonal Antibody to Pyruvate Dehydrogenase Alpha (PDHa)
kl776Mu01 丙酮酸脱氢酶α(PDHα)多克隆抗体 Polyclonal Antibody to Pyruvate Dehydrogenase Alpha (PDHa)
kl776Ra01 丙酮酸脱氢酶α(PDHα)多克隆抗体 Polyclonal Antibody to Pyruvate Dehydrogenase Alpha (PDHa)
kl777Hu01 T-细胞可诱导共刺激分子(ICOS)多克隆抗体 Polyclonal Antibody to Inducible T-Cell Co Stimulator (ICOS)
kl778Hu01 B-细胞**瘤因子2(Bcl2)多克隆抗体 Polyclonal Antibody to B-Cell Leukemia/Lymphoma 2 (Bcl2)
kl778Mu01 B-细胞**瘤因子2(Bcl2)多克隆抗体 Polyclonal Antibody to B-Cell Leukemia/Lymphoma 2 (Bcl2)
kl778Po01 B-细胞**瘤因子2(Bcl2)多克隆抗体 Polyclonal Antibody to B-Cell Leukemia/Lymphoma 2 (Bcl2)
kl778Ra01 B-细胞**瘤因子2(Bcl2)多克隆抗体 Polyclonal Antibody to B-Cell Leukemia/Lymphoma 2 (Bcl2)
kl781Hu01 CD276分子(CD276)多克隆抗体 Polyclonal Antibody to Cluster Of Differentiation 276 (CD276)
